Urea derivatives as calcium channel blockers

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Urea derivatives as calcium channel blockers
United States Patent 7,378,420
Pajouhesh , et al. May 27, 2008
Abstract
Derivatives of urea that contain piperazine rings and additional substitution with aromatic groups are effective in ameliorating conditions associated with unwanted calcium ion channel activity.
Inventors: Pajouhesh; Hassan (Vancouver, CA), Pajouhesh; Hossein (Burnaby, CA), Ding; Yanbing (Vancouver, CA), Snutch; Terrance P. (Vancouver, CA)
Assignee: Neuromed Pharmaceuticals Ltd. (Vancouver, British Columbia, CA)
Appl. No.: 11/215,064
Filed: August 30, 2005