Studies from University of Murcia yield new data on burning mouth syndrome

Studies from University of Murcia yield new data on burning mouth syndrome

2009 FEB 17 -- According to recent research from Murcia, Spain, "To study the efficacy of alpha lipoic acid (ALA) in a group of patients with burning mouth syndrome (BMS). Sixty BMS patients, 30 treated with ALA (Thioderm((R))) 800 mg day(-1) for 8 weeks and 30 patients on the same protocol with a placebo."

"The symptomatology was measured on a Visual Analogue Scale (VAS). Sixty patients (54 females and 6 males, mean age 64.37 +/- 11.61 years) were included. Thirty-nine patients completed the treatment (23 with ALA and 16 with a placebo). Reviews were carried out at 0, 1 and 2 months. No statistically significant differences were found in the average pre- and post-treatment values for pain with the VAS scores, obtained in the placebo (6.6 +/- 2.5 - 2.8 +/- 25 = 3.8 +/- 3.7) versus ALA (6.3 +/- 2.8 - 4.0 +/- 2.7 = 2.2 +/- 2.6). Only one patient pertaining to the group treated with ALA abandoned because of adverse gastrointestinal side effects," wrote P. Lopezjornet and colleagues, University of Murcia.

The researchers concluded: "The results showed no significant differences between the two groups."

Lopezjornet and colleagues published their study in the Journal of Oral Rehabilitation (Efficacy of alpha lipoic acid in burning mouth syndrome: a randomized, placebo-treatment study. Journal of Oral Rehabilitation, 2009;36(1):52-57).

For additional information, contact P. Lopezjornet, University of Murcia, Clinic Odontology University, Medical Bucal Hospital Morales Meseguer, Advanced Marques Velez S-N, Murcia 30008, Spain.

Publisher contact information for the Journal of Oral Rehabilitation is: Blackwell Publishing, 9600 Garsington Rd., Oxford OX4 2DQ, Oxon, England.

Keywords: Spain, Murcia, Burning Mouth Syndrome, Dietary Supplement, Lipoic Acid, Micronutrient, Oral Rehabilitation, Rehabilitation Research, University of Murcia.

This article was prepared by Drug Law Weekly editors from staff and other reports. Copyright 2009, Drug Law Weekly via NewsRx.com.