Sore Mouth
Orf is a zoonotic disease, meaning humans can contract this disorder through direct contact with infected sheep and goats or with fomites carrying the orf virus. It causes a purulent-appearing papule locally and generally no systemic symptoms. Infected locations can include the finger, hand, arm, face and even the penis (caused by infection from the hand during urination). Consequently it is important to observe good personal hygiene and to wear gloves when treating infected animals.[3] The papule may persist for 7 to 10 weeks and spontaneously resolves. It is an uncommon condition and not easily identified by most doctors. This affliction can be contagious (passed from one human to another).

While orf is usually a benign self-limiting illness, it can be very progressive and even life-threatening in the immune-compromised host. One percent topical cidofovir has been successfully used in a few patients with progressive disease. Serious damage may be inflicted on the eye if it is infected by orf, even among healthy individuals. The disease can live in the soil for at least six months.
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