Burning mouth syndrome: the efficacy of lipoic acid on subgroups

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Burning mouth syndrome: the efficacy of lipoic acid on subgroups
2004 Nov;18
Femiano F, Gombos F, Scully C.
PubMed
Stomatology Clinic, II University of Medicine and Surgery, Naples, Italy. femiano@libero.it
OBJECTIVE: We have examined the effect of alpha-lipoic acid (ALA, tioctic acid; Tiobec), a free radical scavenger, on the discomfort of burning mouth syndrome (BMS) in patients who had used tranquillizers previously, compared with those who had not. METHODS: In this study we gave lipoic acid for 2 months to two groups of 20 BMS patients, one of which had previously been treated with tranquillizers. RESULTS: The results showed greater effectiveness of lipoic acid in BMS patients who had not previously used tranquillizers. CONCLUSIONS: The patients with BMS who had previously been treated with tranquillizers responded poorly to therapy with lipoic acid compared with those who had not received previous psychotropic therapy.
PMID: 15482293 [PubMed - indexed for MEDLINE]