Burning mouth syndrome (BMS): sialometric and sialochemical analysis and salivary protein profile
Burning mouth syndrome (BMS): sialometric and sialochemical analysis and salivary protein profile
Authors: Moura, Sérgio Adriane Bezerra de1; Sousa, Jacira Maria Andrade de1; Lima, Dilma Ferreira2; Negreiros, André Newton do Monte2; Silva, Fábio de Vasconcelos2; Costa, Lino João da1
Source: Gerodontology, Volume 24, Number 3, September 2005 , pp. 173-176(4)
Publisher: Blackwell Publishing
Abstract:
Gerodontology 2007; doi: 10.1111/j.1741-2358.2007.00158.x??; ?-?
Burning mouth syndrome (BMS): sialometric and sialochemical analysis and salivary protein profile Objective: 
The aim of the present study was to analyse the characteristics of salivary production and its composition in individuals with burning mouth syndrome (BMS). Study Design: 
Salivary flow rate, concentrations of potassium, iron, chloride, thiocyanate, magnesium, calcium, phosphorus, glucose, total protein and urea, as well as the expression profile of salivary proteins were analysed by SDS-PAGE. Results: 
The mean salivary flow rate among control patients was lower than that of BMS patients. Chloride, phosphorus and potassium levels were elevated in patients with BMS (p = 0.041, 0.001 and 0.034, respectively). Total salivary protein concentration was reduced in individuals with BMS (p  = 0.223). Analysis of the expression of salivary proteins by Coomassie blue SDS-PAGE revealed a lower expression of low molecular weight proteins in individuals with BMS compared to healthy controls. Conclusions: 
These results indicate that the identification and characterisation of low molecular weight salivary proteins in BMS may be important in understanding BMS pathogenesis, thus contributing to its diagnosis and treatment.
Keywords: Burning mouth syndrome; Saliva; Salivary proteins; Sialometry; Sialochemistry
Document Type: Research article
DOI: 10.1111/j.1741-2358.2007.00158.x
Affiliations: 1: Faculdade de Odontologia, Universidade Federal da ParaÃba-João Pessoa, Brazil/Universidade Federal da Bahia, Salvador, Brazil 2: Departamento de BioquÃmica, Universidade Federal do Rio Grande do Norte, Natal, Brazil
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