Bicycloheteroaryl compounds as P2X7 modulators and uses thereof - Burning Mouth Syndrome Patent Applications

Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
United States Patent Application 20070225324
Kind Code A1
Kelly; Michael G. ; et al. September 27, 2007
Abstract
Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
Inventors: Kelly; Michael G.; (Thousand Oaks, CA) ; Kincaid; John; (Belmont, CA) ; Fang; Yunfeng; (Foster City, CA) ; He; Jianhua; (Foster City, CA) ; Cao; Yeyu; (Foster City, CA) ; Kaub; Carl; (San Mateo, CA) ; Gowlugari; Sumithra; (San Mateo, CA) ; Wang; Zhan; (Palo Alto, CA)
Correspondence Name and Address:
KLAUBER & JACKSON
411 HACKENSACK AVENUE
HACKENSACK
NJ
07601
US

Serial No.: 725153
Series Code: 11
Filed: March 16, 2007

U.S. Current Class: 514/309; 546/143
U.S. Class at Publication: 514/309; 546/143
Intern'l Class: A61K 31/4704 20060101 A61K031/4704; C07D 217/22 20060101 C07D217/22