MEDLINEÂ® (Medical Literature Analysis and Retrieval System Online) is the U.S. National Library of Medicine'sÂ® (NLM) premier bibliographic database that contains over 16 million references to journal articles in life sciences with a concentration on biomedicine. A distinctive feature of MEDLINE is that the records are indexed with NLM's Medical Subject Headings (MeSHÂ®).
The great majority of journals are selected for MEDLINE based on the recommendation of the Literature Selection Technical Review Committee (LSTRC), an NIH-chartered advisory committee of external experts analogous to the committees that review NIH grant applications. Some additional journals and newsletters are selected based on NLM-initiated reviews, e.g., history of medicine, health services research, AIDS, toxicology and environmental health, molecular biology, and complementary medicine, that are special priorities for NLM or other NIH components. These reviews generally also involve consultation with an array of NIH and outside experts or, in some cases, external organizations with which NLM has special collaborative arrangements.
MEDLINE is the primary component of PubMedÂ®, part of the Entrez series of databases provided by NLM's National Center for Biotechnology Information (NCBI). MEDLINE may also be searched via the NLM Gateway.