Burning mouth syndrome responsive to pramipexol.

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Burning mouth syndrome responsive to pramipexol.
J. Stuginski-Barbosa1, G. G. R. Rodrigues1, M. E. Bigal2 and J. G. Speciali1, 3 Contact Information
(1) The Department of Neurology, School of Medicine at Ribeirão Preto, Ribeirão Preto, SP, Brazil
(2) Neurology, The Albert Einstein College of Medicine, Bronx, NY, USA
(3) Hospital das Clínicas de Ribeirão Preto, Avenida Bandeirantes, 3900, Ribeirão Preto, SP, 14400-000, Brazil

Received: 7 September 2007 Accepted: 25 November 2007 Published online: 25 January 2008

Abstract

Burning mouth syndrome (BMS) is characterized by burning discomfort or pain in otherwise normal oral mucosa. It is usually refractory. Treatment modalities are scarce. Herein we report one case of primary disabling BMS, previously refractory to multiple regimens, with complete and persistent improvement with pramipexol, a nonergot dopamine agonist which has high selectivity for dopaminergic D2 receptors. We discuss potential pathophysiological implications of our findings.


The journal of headache and pain 2008 Feb